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Antigenic Specificity | Mouse IL-13Rα2 (BA) |
Clone | W19369C |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | purified, low endotoxin, azide-free |
Size | 1 mg |
Concentration | n/a |
Applications | Neut |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-mouse IL-13Rα2 (BA). IL-13 is a key mediator in the pathogenesis of allergic inflammation. Its receptor is comprised of IL-4Rα and IL-13Rα1, which transduct the signaling to the downstream STAT6 pathway. IL-13Rα2, also known as IL-13Ra2 and IL-13BP, serves as a decoy receptor to attenuate IL-13-induced response. IL-13Rα2 binds IL-13 with 100-300 folds higher affinity than does IL-13Rα1, but IL-13Rα2 lacks signaling motifs on its cytoplasmic tail. Mice deficient in IL-13Rα2 showed increased IgE level and IFNγ product |
Immunogen | Recombinant mouse IL-13Rα2-Fc chimera |
Other Names | Interleukin-13 receptor subunit alpha-2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, IL-13R alpha-2, IL-13Rα2, IL-13Ra2, CD213a2, IL-13 binding protein, IL-13BP |
Gene, Accession # | Gene ID: 16165 |
Catalog # | 947904 |
Price | $1205 |
Order / More Info | Mouse IL-13Rα2 (BA) Antibody from BIOLEGEND |
Product Specific References | n/a |