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Antigenic Specificity | Mouse CD357 (GITR) |
Clone | YGITR 765 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, κ |
Format | PE-Cyanine7 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cyanine7 anti-mouse CD357 (GITR). GITR, Glucocorticoid-induced TNFR-related gene, is a member of the TNF receptor superfamily, also known as TNFRSF18, and AITR (in humans). It is expressed at low levels on resting T lymphocytes and at high levels on CD4 CD25 T regulatory (Treg) cells. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation, and ab |
Immunogen | Recombinant mouse GITR protein and Transfected cells |
Other Names | TNFRSF18, AITR |
Gene, Accession # | Gene ID: 21936 |
Catalog # | 120222 |
Price | $347 |
Order / More Info | Mouse CD357 (GITR) Antibody from BIOLEGEND |
Product Specific References | PubMed: 31043609, 30131376, 31875552, 32640259 |