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Antigenic Specificity | EGFR |
Clone | A18011A |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP, Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-EGFR. Epidermal Growth Factor Receptor (EGFR) is a receptor tyrosine kinase that links extracellular mitogenic ligand binding to complex downstream signaling cascades. Initial ligand binding results in receptor oligomerization and autophosphorylation of multiple tyrosine residues within cytosolic domains of the the protein. These phosphorylation events stabilize the EGFR kinase activation loop and lead to the recruitment of adaptor proteins and other downstream effectors. EGFR stimulation leads to act |
Immunogen | Synthetic peptide corresponding to human EGFR surrounding Tyrosine 869 (Tyrosine 845 if signal peptide is excluded) |
Other Names | Epidermal Growth Factor Receptor, Receptor Tyrosine-Protein Kinase ErbB-1, Erb-B2 Receptor Tyrosine Kinase 1, ERBB1, NISBD2, PIG61, MENA |
Gene, Accession # | Gene ID: 1956 |
Catalog # | 617501 |
Price | $101 |
Order / More Info | EGFR Antibody from BIOLEGEND |
Product Specific References | n/a |