Cleaved PARP (Asp214) Recombinant Antibody from BIOLEGEND

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Antigenic SpecificityCleaved PARP (Asp214) Recombinant
CloneQA17A17
Host SpeciesRecombinant Mouse
Reactive Specieshuman
IsotypeIgG1, κ
Formatallophycocyanin (APC) conjugate
Size100 tests
Concentrationn/a
ApplicationsIntracellular Staining for Flow Cytometry (ICFC)
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DescriptionAPC anti-Cleaved PARP (Asp214) Recombinant. PARP (ADP-Ribose) Polymerase (PARP) is a 113 kD nuclear protein important for mediating the normal cellular response to DNA damage and repair in response to environmental stress. PARP catalyzes the transfer of ADP-ribose units from NAD? to various nuclear proteins, including topoisomerases, histones, and PARP itself, by poly(ADP-ribosyl)ation. Following DNA damage, this protein is cleaved by ICE-like caspases, such as caspase-3 and -7. In humans, this PARP cleavage occurs between Asp214 and Gly2
ImmunogenProprietary synthetic peptide
Other NamesPARP1, Poly (ADP-ribose) polymerase, PPOL, ARTD1, ADPRT, EC 2.4.2, ADP-Ribosyltransferase (NAD+;Poly (ADP-Ribose) Polymerase), Poly (ADP-Ribose) Polymerase Family, Member 1, DNA ADP-Ribosyltransferase PARP1, Poly[ADP-Ribose] Synthase 1
Gene, Accession #Gene ID: 142
Catalog #669910
Price$379
Order / More InfoCleaved PARP (Asp214) Recombinant Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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