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Antigenic Specificity | Human CD243 (MDR-1) |
Clone | UIC2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | Alexa Fluor® 594 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 594 anti-human CD243 (MDR-1). CD243 (MDR-1) belongs to the ATP binding cassette (ABC) transporter family. With an approximate molecular mass of 170 kD, it consists of two homologous halves. Each half contains two hydrophobic transmembrane domains (TMDs) and two hydrophilic nucleotide binding domains (NBDs). The TMDs span the membrane six times, forming a chamber with a 12 transmembrane α-helix structure. NBDs drive the transport process through ATP coupling and hydrolysis and are located at the cytoplasmic face of the membra |
Immunogen | NIH 3T3 cells transfected with human MDR-1 cDNA |
Other Names | Multidrug resistance protein 1, ATP-binding cassette sub-family B member 1, P-glycoprotein 1 |
Gene, Accession # | Gene ID: 5243 |
Catalog # | 348616 |
Price | $347 |
Order / More Info | Human CD243 (MDR-1) Antibody from BIOLEGEND |
Product Specific References | n/a |