Description | Purified anti-human CD123. CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CD131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |
Product Specific References | PubMed: 20357241, 19517126, 22429820, 29466759, 30142345, 29605184, 30982598, 29466759, 30982598, 30142345, 29605184, 29466759, 28475900, 28368000, 29605184, 31940481, 31474370, 30778347, 31240276, 31949260, 33111099, 33177106, 32470397, 33521697, 33748804, 33977279, 34143954 |