Nicastrin Antibody from BIOLEGEND

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Antigenic SpecificityNicastrin
Clone9C3
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2b, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blot (WB), IHC-P
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPurified anti-Nicastrin. Nicastrin is one of the essential components of the γ-secretase complex. The γ-secretase complex is one of the proteases involved in processing amyloid precursor protein (APP) to amyloid beta (Aβ). Nicastrin is not catalytically active, instead, it promotes the maturation and localization of other catalytic and regulatory units of the γ-secretase complex. Nicastrin has alsp been reported to regulate neprilysin, which is the enzyme involved in the degradation of Aβ fragment.
ImmunogenSynthetic peptide corresponding to the C-terminal 18 a.a. of mouse Nicastrin.
Other NamesNCSTN
Gene, Accession #Gene ID: 23385
Catalog #852302
Price$276
Order / More InfoNicastrin Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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http://www.biolegend.com

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