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Antigenic Specificity | Human CD274 (B7-H1, PD-L1) |
Clone | 29E.2A3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human CD274 (B7-H1, PD-L1). CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation |
Immunogen | Full length human PD-L1 |
Other Names | Programmed cell death ligand 1 (PD-L1), B7 homolog 1 (B7-H1) |
Gene, Accession # | Gene ID: 29126 |
Catalog # | 329705 |
Price | $118 |
Order / More Info | Human CD274 (B7-H1, PD-L1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 21057085, 22661084, 24875729, 26323609, 26780292, 27342848, 27539532, 27762298, 28057926, 29765028, 29844835, 29937998, 29993362, 29996099, 30290143, 30426611, 29097421, 30956773, 31133636, 31379842, 30917314, 30290143, 29996099, 29993362, 30555457, 31883921, 29069824, 28561041, 31399559, 32579541, 32579541, 32988398, 33330050, 33303017, 33010815, 32528882, 32539182, 32391629, 31486697, 33490159, 33628210, 32504554, 33010815, 33378668, 33490159, 33909988 |