Description | Brilliant Violet 421™ anti-mouse CD3. CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex |
Product Specific References | PubMed: 25663343, 26423148, 26619277, 26467188, 29343433, 31413918, 29101162, 31273194, 30650377, 31526760, 30650377, 31053504, 28240810, 29126435, 31526760, 32117252, 32214351, 31001257, 30917315, 30712876, 32647297, 32220307, 31813625, 32778803, 31986485, 33798472 |