Edit |   |
---|---|
Antigenic Specificity | Human CD223 (LAG-3) |
Clone | 7H2C65 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-human CD223 (LAG-3). CD223, also known as LAG-3, is a 70 kD type I transmembrane glycoprotein that is involved in T-cell signaling. Similar to CD4, CD223 binds MHC class II, but with a higher affinity. CD223 negatively regulates T-cell activation. It is expressed by activated T-cells and natural killer cells (NKs), as well as regulatory T-cells. It is transiently expressed on the surface of activated T-cells in acute conditions but high expression is maintained under tolerizing conditions. CD223 deficiency results i |
Immunogen | Human LAG-3 transfected cells. |
Other Names | CD223, LAG-3, LAG3, lymphocyte-activation gene-3 |
Gene, Accession # | Gene ID: 3902 |
Catalog # | 369204 |
Price | $399 |
Order / More Info | Human CD223 (LAG-3) Antibody from BIOLEGEND |
Product Specific References | n/a |