Edit |   |
---|---|
Antigenic Specificity | Human Tim-4 |
Clone | 9F4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | TotalSeq™-C oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | PG |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-C0428 anti-human Tim-4. The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th-1 and Th-2) cell-mediated immunity. Tim-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of Tim-1. This binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, Tim-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. |
Immunogen | Human TIM-4- IgV Fc, fusion protein |
Other Names | SMUCKLER (Spleen, mucin-containg, knock-out of lymphotoxin (LT)), TIMD4 (T-cell immunoglobulin and mucin domain containing 4) |
Gene, Accession # | Gene ID: 91937 |
Catalog # | 354013 |
Price | $369 |
Order / More Info | Human Tim-4 Antibody from BIOLEGEND |
Product Specific References | n/a |