Description | PE/Cyanine5 anti-mouse CD3ε. CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
Product Specific References | PubMed: 19629186, 20530790, 24719427, 25472997, 29336307, 29363729, 30332631, 29695863, 30540934, 30827134, 29166591, 31167130, 30332631, 30561324, 28583252, 30975913, 31474573, 31801074, 29958801, 32359443, 31871120, 33761361 |