CD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3) Antibody from BIOLEGEND

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Antigenic SpecificityCD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3)
CloneC219
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1, κ
Formatpurified
Size1 mL
Concentrationn/a
ApplicationsIHC-P, Western Blot (WB), IHC-F, ICC, ELISA, Flow Cytometry (FC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPurified anti-CD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3). Clone C219 recognizes an internal, highly conserved amino acid sequence (VQEALD & VQAALD) found in both MDR1 and MDR3 isoforms of P-glycoprotein. The specific binding of the clone C219 was stronger in epitope sequence VQAALD (N-Terminal fragment) than the epitope sequence VQEALD (C-terminal fragmant) (Georges E., et al., 1990). Analysis of p-glycoprotein expression in skeletal and cardiac muscle revealed that C219 cross reacts with a 200kDa protein that migrates in the same position as myosin. C
ImmunogenThis antibody was made against SDS-solubilized plasma membranes of a multidrug resistant Chinese hamster ovary (CHO) cell line and a human cell line.
Other NamesMultidrug resistance protein 3, P-glycoprotein 3, multiple drug resistance 3, ATP-binding cassette sub-family B member 4, P glycoprotein 3/multiple drug resistance 3
Gene, Accession #Gene ID: 5244
Catalog #903701
Price$604
Order / More InfoCD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 8646690, 8674056, 27792760, 30217571, 30217571, 30396915
BIOLEGEND
BIOLEGEND
BIOLEGEND
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