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Antigenic Specificity | CD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3) |
Clone | C219 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 1 mL |
Concentration | n/a |
Applications | IHC-P, Western Blot (WB), IHC-F, ICC, ELISA, Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-CD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3). Clone C219 recognizes an internal, highly conserved amino acid sequence (VQEALD & VQAALD) found in both MDR1 and MDR3 isoforms of P-glycoprotein. The specific binding of the clone C219 was stronger in epitope sequence VQAALD (N-Terminal fragment) than the epitope sequence VQEALD (C-terminal fragmant) (Georges E., et al., 1990). Analysis of p-glycoprotein expression in skeletal and cardiac muscle revealed that C219 cross reacts with a 200kDa protein that migrates in the same position as myosin. C |
Immunogen | This antibody was made against SDS-solubilized plasma membranes of a multidrug resistant Chinese hamster ovary (CHO) cell line and a human cell line. |
Other Names | Multidrug resistance protein 3, P-glycoprotein 3, multiple drug resistance 3, ATP-binding cassette sub-family B member 4, P glycoprotein 3/multiple drug resistance 3 |
Gene, Accession # | Gene ID: 5244 |
Catalog # | 903701 |
Price | $604 |
Order / More Info | CD243/ABCB4 (ABCB1, P-glycoprotein1/MDR3) Antibody from BIOLEGEND |
Product Specific References | PubMed: 8646690, 8674056, 27792760, 30217571, 30217571, 30396915 |