Edit |   |
---|---|
Antigenic Specificity | Mouse IFNAR-1 |
Clone | MAR1-5A3 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | biotin conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP, Western Blot (WB), ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Biotin anti-mouse IFNAR-1. IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associat |
Immunogen | Exogenously expressed murine IFNAR1 extracellular domain |
Other Names | IFNAR1, IFN-αR1, IFN-α/β Receptor Subunit 1 |
Gene, Accession # | Gene ID: 15975 |
Catalog # | 127305 |
Price | $89 |
Order / More Info | Mouse IFNAR-1 Antibody from BIOLEGEND |
Product Specific References | PubMed: 32049051 |