Description | Brilliant Violet 421™ anti-mouse CD3ε. CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
Product Specific References | PubMed: 26399548, 26851186, 29250074, 29426702, 30788384, 30510995, 30970254, 30971695, 29288079, 30970254, 31097342, 29426702, 28514690, 29120744, 31930167, 31479431, 31527834, 31736917, 31668803, 30021726, 32821819, 34125490, 33852868, 34077722 |