Description | Alexa Fluor® 488 anti-mouse/human CD11b. CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. |
Product Specific References | PubMed: 17259380, 20164456, 23497256, 25172500, 26098692, 26475734, 27059596, 27197197, 27549169, 27566823, 28442605, 28498310, 29058703, 28498310, 29241547, 29436030, 29993362, 30559930, 30820451, 29111308, 30628675, 30840892, 30873298, 30910700, 30926232, 30947238, 31246581, 30811982, 31392695, 31358739, 30870621, 30926232, 30811982, 30840892, 29436030, 29993362, 28803730, 32198351, 30870621, 30862706, 31851943, 31839486, 32923118, 32586353, 33039895, 33101269, 32489699, 32251383, 33213476, 32692155, 33098765, 33826903 |