Human Siglec-8 Antibody from BIOLEGEND

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Antigenic SpecificityHuman Siglec-8
Clone7C9
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, κ
FormatPE-Cyanine5 conjugate
Size25 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC)
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DescriptionPE/Cyanine5 anti-human Siglec-8. Siglec-8 is a lectin specific for 6?-sulfo-sLex and a member of the Ig-superfamily. It is expressed almost exclusively in eosinophils; however, basophils and mast cells can express it to a lower degree. Siglec-8 is a 54 kD transmembranal protein; the extracellular domain has one V-set Ig-like domain and two C2-set domains. The cytoplasmic domain has two immunoreceptor tyrosine-based inhibitor motifs (ITIM) that recruit SH2-family phosphatases after tyrosine phosphorylation. There are reports tha
ImmunogenRecombinant Siglec-8 fused to human IgG Fc
Other NamesSialic acid-binding Ig-like lectin 8 (Siglec-8), Siglec8L, Sialoadhesin family member 2 (SAF2)
Gene, Accession #Gene ID: 27181
Catalog #347113
Price$183
Order / More InfoHuman Siglec-8 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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