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Antigenic Specificity | Human Siglec-8 |
Clone | 7C9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | PE-Cyanine5 conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cyanine5 anti-human Siglec-8. Siglec-8 is a lectin specific for 6?-sulfo-sLex and a member of the Ig-superfamily. It is expressed almost exclusively in eosinophils; however, basophils and mast cells can express it to a lower degree. Siglec-8 is a 54 kD transmembranal protein; the extracellular domain has one V-set Ig-like domain and two C2-set domains. The cytoplasmic domain has two immunoreceptor tyrosine-based inhibitor motifs (ITIM) that recruit SH2-family phosphatases after tyrosine phosphorylation. There are reports tha |
Immunogen | Recombinant Siglec-8 fused to human IgG Fc |
Other Names | Sialic acid-binding Ig-like lectin 8 (Siglec-8), Siglec8L, Sialoadhesin family member 2 (SAF2) |
Gene, Accession # | Gene ID: 27181 |
Catalog # | 347113 |
Price | $183 |
Order / More Info | Human Siglec-8 Antibody from BIOLEGEND |
Product Specific References | n/a |