Description | APC anti-mouse CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activatio |
Product Specific References | PubMed: 21131560, 24958905, 26115685, 26699463, 27311945, 29691463, 30291028, 30393066, 29343435, 30170810, 30718511, 31167130, 31409776, 31324770, 31350178, 30770245, 30291028, 30170810, 29343435, 30393066, 31112525, 31553907, 31549585, 32042338, 31577946, 32111828, 32142554, 32226779, 32256652, 32442402, 32929072, 32923651, 32923626, 33106640, 33164745, 32665441, 32406154, 33537243, 33909988 |