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Antigenic Specificity | NLRP1 |
Clone | 9F9B12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-NLRP1. NLRP1, also known as NALP1, is a member of the NOD-like receptor (NLR) family that is responsible for the recognition of pathogen-associated molecular patterns (PAMP). NLRP1 is a sensor component of inflammasome that is involved in innate immune response. NLRP1-dependent activation of caspase-1 drives rapid proteolytic activation of caspase-1 and the maturation of the proinflammatory cytokines IL-1β and IL-18. The activation of NLRP1 leads to cell death of macrophages via pyroptosis, which resul |
Immunogen | Partial human NLRP1 recombinant protein (1-200 a.a.) expressed in E. coli. |
Other Names | NLR Family, Pyrin Domain Containing 1, NALP1, Caspase Recruitment Domain-Containing Protein 7 (CARD7), Systemic Lupus Erythematosus, Vitiligo-Related 1 (SLEV1), NAC, CIDED, NALP1, DEFCAP, PP1044, VAMAS1, CLR17.1, DEFCAP-L/S |
Gene, Accession # | Gene ID: 22861 |
Catalog # | 679802 |
Price | $288 |
Order / More Info | NLRP1 Antibody from BIOLEGEND |
Product Specific References | PubMed: 27993998, 32840892 |