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Antigenic Specificity | Human CD274 (B7-H1, PD-L1) |
Clone | 29E.2A3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IHC-P, Block |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD274 (B7-H1, PD-L1). CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation |
Immunogen | Full length human PD-L1 |
Other Names | Programmed cell death ligand 1 (PD-L1), B7 homolog 1 (B7-H1) |
Gene, Accession # | Gene ID: 29126 |
Catalog # | 329701 |
Price | $59 |
Order / More Info | Human CD274 (B7-H1, PD-L1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 24336068, 26351349, 27572267, 29559973, 30679441, 31379843, 31262041, 30012633, 31141680, 28475900, 28592566, 28938530, 29382670, 29538651, 30405617, 30541986, 28943329, 28813417, 30941141, 31399559, 32483468, 29339539, 31949260, 33070512, 34174183 |