Description | PE anti-mouse CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activatio |
Product Specific References | PubMed: 16517712, 24443555, 24625653, 25295996, 26170030, 26537633, 27812214, 28129129, 28236573, 28964723, 29127106, 29662125, 29773802, 29867097, 29922290, 29942258, 29548673, 30992475, 29934320, 31222014, 31475002, 31275292, 31542340, 28636953, 30023513, 31896526, 32578719, 32363119, 31727773, 32676336, 30292939, 31778579, 32814898, 31130955, 31851905, 33053342, 33086073, 32579940, 32424368, 32888430, 33053342, 33515487 |