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Antigenic Specificity | Human CD77 |
Clone | 5B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), Western Blot (WB), IHC-F |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD77. CD77 is also known as Gb3 glycosphingolipid. It was found specifically expressed on Burkitt?s lymphoma cells and on a subset of germinal center B lymphocytes. CD77 has been described as a receptor for Shiga Toxin and Verotoxin 1 (VT1), which is produced by Shigella dysenteriae and some strains of E. coli. It is used as a marker for germinal center stage B-cells. CD19 has been reported as a ligand for D77 and their interaction functions in adhesion and signal transduction at a specific stage of B |
Immunogen | Human peripheral blood mononuclear cells |
Other Names | globotriaosylcermamide (Gb3), Burkitt?s lymphoma associated antigen (BLA), cermadie trihexoside (CTH), and Pk blood group antigen |
Gene, Accession # | Gene ID: 53947 |
Catalog # | 357101 |
Price | $65 |
Order / More Info | Human CD77 Antibody from BIOLEGEND |
Product Specific References | PubMed: 31970091 |