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Antigenic Specificity | MyD88 |
Clone | O91B8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-MyD88. MyD88, originally isolated as myeloid differentiation primary response gene, is expressed in a variety of tissues. MyD88 serves as a cytoplasmic adaptor protein involved in the signaling of TLR and IL-1R family members. It associates with and recruits IRAK to IL-1R complex in response to IL-1. This pathway leads to activation of NF-kB. Targeted disruption of the MyD88 gene results in loss of cellular responses to IL-1 and IL-18. MyD88 deficient mice lack a response to LPS (a bacterial product) |
Immunogen | Full length recombinant MyD88 protein produced in 293T cells. |
Other Names | Myeloid Differentiation Primary Response Protein MyD88, MYD88D |
Gene, Accession # | Gene ID: 4615 |
Catalog # | 675802 |
Price | $229 |
Order / More Info | MyD88 Antibody from BIOLEGEND |
Product Specific References | PubMed: 29691463 |