Description | PE/Cyanine7 anti-human CD123. CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CD131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |
Product Specific References | PubMed: 19956772, 22351936, 22720031, 24155390, 24399813, 24915147, 25075741, 25156368, 26382296, 27705789, 29411522, 29478914, 30245083, 30270043, 30705679, 30680014, 29997203, 30765193, 28031160, 30765193, 30270043, 30245083, 29478914, 28320838, 30719121, 31937836, 31491384, 33037195, 33377019, 32849574, 33790912, 33450207, 34214472 |