Edit |   |
---|---|
Antigenic Specificity | Human IL-18BP |
Clone | W19089C |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, λ |
Format | purified, low endotoxin, azide-free |
Size | 100 µg |
Concentration | n/a |
Applications | Neut |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-human IL-18BP. IL-18 binding protein (IL-18BP) binds to IL-18 with high affinity (Kd = 400 pM), neutralizes IL-18 activity and binds to IL-18 in a stoichiometric ratio. IL-18 belongs to the Interleukin-1 family and is a potent inflammatory cytokine. IL-18 is secreted by macrophages and dendritic cells and is expressed constitutively even in the absence of an inflammatory stimulus. IL-18 induces IFN-γ production, in the presence of IL-12 or IL-15, from Th1 cells. In addition, IL-18 promotes FasL-mediated cytoto |
Immunogen | Recombinant human IL-18BP |
Other Names | IL18 BPa, IL-18 BPa, IL18BP, IL-18BP, IL18BPa; interleukin 18 binding protein, interleukin-18-binding protein, MC51L-53L-54L homolog gene product; tadekinig-alfa |
Gene, Accession # | Gene ID: 10068 |
Catalog # | 947703 |
Price | $358 |
Order / More Info | Human IL-18BP Antibody from BIOLEGEND |
Product Specific References | n/a |