Caspase-1 Antibody from BIOLEGEND

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Antigenic SpecificityCaspase-1
Clone5B10
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a, κ
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsWestern Blot (WB), IHC
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DescriptionPurified anti-Caspase-1. Caspase -1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17 kd mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45 Kd. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large amino-terminal pro-domain and a small linker peptide. Caspase-1 is reported to be involved in CD95- mediated apoptosis. Four alternatively spliced variants of caspase-1 have been r
ImmunogenBacterial fusion protein (p20)
Other NamesICE
Gene, Accession #Gene ID: 834
Catalog #645101
Price$124
Order / More InfoCaspase-1 Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 26764201, 27993998
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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