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Antigenic Specificity | TAB1 |
Clone | W15153A |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), KO/KD-Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-TAB1. TAB1 (TGFβ-Activated Kinase 1-Binding Protein 1), also known as TAK1-Binding Protein 1, is a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which mediates MAPK signaling pathways and proinflammatory signaling induced by TGF-β, IL-1, TNF-α and WNT-1. In the signaling pathway triggered by TGF- β, the binding of TAB1 and TAK1 triggers TAK1 autophosphorylation and activation. In the response to TNF-α or IL-1, TAK1 binds with TAB1/TAB2 or TAB1/TAB3 to form distinct complexes. In addition, TA |
Immunogen | Partial human TAB1 recombinant protein (255-504 a.a.) expressed in E. coli. |
Other Names | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, Mitogen-activated protein kinase, kinase 7-interacting protein 1 (MAP3K7IP1), TGF-beta-activated kinase 1-binding protein 1, TAK1-binding protein 1, 3?-Tab1 |
Gene, Accession # | Gene ID: 10454 |
Catalog # | 687902 |
Price | $229 |
Order / More Info | TAB1 Antibody from BIOLEGEND |
Product Specific References | n/a |