Edit |   |
---|---|
Antigenic Specificity | Mouse Aiolos |
Clone | 8B2 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), Intracellular Staining for Flow Cytometry (ICFC), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse Aiolos. Aiolos, an Ikaros family member, is also known as Izkf3. It has a molecular weight of 58 kD and shows 70% homology to the Ikaros isoform, Ik-1, particularly in the DNA binding and C-terminal domains. Aiolos can form a heteromer with Ikaros or exist as a homodimer. The homomeric complex is a potent transcriptional activator. Unlike Ikaros, Aiolos is expressed in late fetal thymus and adult lymphoid organs. Among the adult hematopoietic progenitors, Aiolos is expressed at low levels in mulitpoten |
Immunogen | N-terminal half of mouse Aiolos fused to GST |
Other Names | IKAROS family zinc finger 3 (Ikzf3), zinc finger protein Aiolos, Zfpn1a3, Znfn1a3 |
Gene, Accession # | Gene ID: 22780 |
Catalog # | 653201 |
Price | $141 |
Order / More Info | Mouse Aiolos Antibody from BIOLEGEND |
Product Specific References | PubMed: 30926234 |