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Antigenic Specificity | ATF4 |
Clone | W16016A |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-ATF4. The ER responds to the accumulation ofunfolded proteins in its lumenby activating intracellular signaling pathways, which is collectively termed the unfolded protein response (UPR). Three major branches of the UPR have been identified, including IRE1 (inositol requiring enzyme 1), PERK [double-stranded RNA-activated protein kinase (PKR)-like ER kinase], and ATF6 (activating transcription factor 6). The second branch of the UPR is mediated by PERK. Upon activation, PERK oligomerizes and phosphory |
Immunogen | Partial human ATF4 (102-351 a.a.) expressed in E. coli. |
Other Names | Activating transcription factor 4, Cyclic AMP-dependent transcription factor ATF-4, CREB-2, DNA-binding protein TAXREB67 |
Gene, Accession # | Gene ID: 468 |
Catalog # | 693902 |
Price | $276 |
Order / More Info | ATF4 Antibody from BIOLEGEND |
Product Specific References | PubMed: 28744854, 31257153 |