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Antigenic Specificity | Rb |
Clone | W18116A |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IP, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Rb. Rb is a key regulator of the cell cycle, more specifically during the transition from the G1 to S phases. The underphosphorylated, active form of Rb interacts directly with E2F1, leading to cell cycle arrest, while the hyperphosphorylated form decouples from E2F1, thus promoting the transcription of genes promoting entry into the S phase. Rb is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by sta |
Immunogen | Partial recombinant human Rb protein. |
Other Names | RB Transcriptional Co-repressor 1, Retinoblastoma-Associated Protein, Protein Phosphate 1, Regulatory Subunit 130 |
Gene, Accession # | Gene ID: 5925 |
Catalog # | 933402 |
Price | $253 |
Order / More Info | Rb Antibody from BIOLEGEND |
Product Specific References | n/a |