Human EGFR Antibody from BIOLEGEND

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Antigenic SpecificityHuman EGFR
CloneAY13
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, κ
FormatBrilliant Violet 711™ conjugate
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC)
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DescriptionBrilliant Violet 711™ anti-human EGFR. Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and member of the protein kinase superfamily that regulates cell growth and differentiation. EGFR binds EGF, TGF-α, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30, and vaccinia virus growth factor - all members of the EGF family. Ligand binding induces EGFR dimerization and autophosphorylation, initiating the MAPK, Akt, and JNK signaling pathways. EGFR is expressed by epithelial and endothelial cell
ImmunogenNon-small cell lung cancer (NSCLC) cell line NCI-H322
Other NamesProto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, HER1
Gene, Accession #Gene ID: 1956
Catalog #352920
Price$429
Order / More InfoHuman EGFR Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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