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Antigenic Specificity | Tau Phospho (Thr181) |
Clone | M7004D06 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | IHC-P, Direct ELISA, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Tau Phospho (Thr181). Tau protein promotes microtubule assembly and stability. Tau is abundant in neurons of the central nervous system, and is expressed at low levels in astrocytes and oligodendrocytes. Abnormal hyper-phosphorylation, aggregation, and toxic gain of function of tau is associated with several neurological disorders, including Alzheimer's disease (AD). The major building block of neurofibrillary lesions in AD brains consists of paired helical filaments (PHFs) of abnormally hyperphosphorylated tau. Rece |
Immunogen | 15-mer pT181 Tau peptide conjugated to KLH. |
Other Names | Microtubule associated protein tau |
Gene, Accession # | Gene ID: 4137 |
Catalog # | 846601 |
Price | $112 |
Order / More Info | Tau Phospho (Thr181) Antibody from BIOLEGEND |
Product Specific References | PubMed: 31913282 |