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Antigenic Specificity | Human CD274 (B7-H1, PD-L1) |
Clone | 29E.2A3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | allophycocyanin (APC) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-human CD274 (B7-H1, PD-L1). CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation |
Immunogen | Full length human PD-L1 |
Other Names | Programmed cell death ligand 1 (PD-L1), B7 homolog 1 (B7-H1) |
Gene, Accession # | Gene ID: 29126 |
Catalog # | 329707 |
Price | $138 |
Order / More Info | Human CD274 (B7-H1, PD-L1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 23095323, 24812408, 26069249, 26014098, 26822383, 27624143, 27474072, 27802341, 30061941, 29867997, 29765039, 30290143, 28167507, 30713786, 31460379, 31291716, 29141863, 31415244, 30290143, 28810147, 29858049, 31305264, 31331945, 31935881, 31577944, 30564890, 30842489, 32195027, 32493985, 32668238, 29789418, 32647108, 30221065, 30555458, 31467059, 33330050, 33133253, 32823915, 33399495 |