Human/Mouse CD3ε (activation epitope) Antibody from BIOLEGEND
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| Antigenic Specificity | Human/Mouse CD3ε (activation epitope) |
| Clone | APA1/1 |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1, κ |
| Format | purified |
| Size | 500 µg |
| Concentration | n/a |
| Applications | Intracellular Staining for Flow Cytometry (ICFC), Western Blot (WB), IHC-P, in-vivo Cell Tracking, ICC, IHC, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-human/mouse CD3ε (activation epitope). The CD3ε chain of the CD3-TCR complex is a type I membrane protein that undergoes conformational change following ligation of the TCR-CD3 complex. This conformational change leads to exposure of the proline rich sequence in CD3ε and results in recruitment of Nck. It is expressed by all mature T cells and forms a heteromeric complex with CD3 α/β or γ/δ and ζ chains. It is important in T cell development, and deficiency of this gene has been associated with severe immunodeficiency. |
| Immunogen | Purified denatured CD3 proteins from human thymus |
| Other Names | CD3e molecule, epsilon (CD3-TCR complex), CD3e antigen, CD3 epsilon |
| Gene, Accession # | Gene ID: 916 |
| Catalog # | 362702 |
| Price | $258 |
| Order / More Info | Human/Mouse CD3ε (activation epitope) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 32550901 |
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