Description | Purified anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 28732035, 28732035, 29167449, 29031634, 31036155, 28503929, 28615199, 28674533, 28869974, 28938530, 28945199, 29248757, 29468194, 29858049, 31036155, 29187589, 29411179, 31168092, 30778347, 31348886, 32160548, 31833593, 31982038, 32553276 |