TSC2 Antibody from BIOLEGEND
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| Antigenic Specificity | TSC2 |
| Clone | W16104A |
| Host Species | Rat |
| Reactive Species | human, mouse |
| Isotype | IgG2a, κ |
| Format | purified |
| Size | 25 µg |
| Concentration | n/a |
| Applications | Western Blot (WB), KO/KD-Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-TSC2. Tuberous sclerosis 2 (TSC2) forms the tuberous sclerosis complex with TSC1 and functions as a crucial negative regulator of the Rheb/mTOR pathway. mTOR belongs to the PI3K-related kinase family and regulates protein translation, cell proliferation, and cell differentiation. Activation of mTOR requires binding to the active small GTPase Ras homolog enriched in brain (Rheb). TSC2 acts as a GTPase activating protein (GAP) and inhibits mTORC1 through converting active GTP-bound Rheb to inactive GDP- |
| Immunogen | Human TSC2 recombinant protein (1508-1807 amino acid) expressed in E. coli. |
| Other Names | Tuberin, Tuberous sclerosis 2 protein, TSC4 |
| Gene, Accession # | Gene ID: 7249 |
| Catalog # | 697701 |
| Price | $101 |
| Order / More Info | TSC2 Antibody from BIOLEGEND |
| Product Specific References | n/a |
BIOLEGEND
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