Description | Brilliant Violet 785™ anti-human CD8a. CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation, and has been shown to play a role in thymic differentiation. |
Product Specific References | PubMed: 28476239, 28476239, 28993513, 29398219, 29895574, 30770246, 29739909, 31968246, 32047491, 30770246, 32671116, 32750333, 31730855, 31761718, 32868758, 32739778, 32708557, 33772147, 32640259, 33248023, 33306960, 33910015 |