Human CD41/CD61 Antibody from BIOLEGEND
Search, find, compare suppliers for anti-Human CD41/CD61 antibody, protein, ELISA kits.
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| Antigenic Specificity | Human CD41/CD61 |
| Clone | PAC-1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC), IP, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-human CD41/CD61. The gpIIb/IIIa complex, also known as integrin αIIbβ3, is expressed by megakaryocytes and platelets. It undergoes conformational changes upon activation by substances, such as ADP, thrombin, and TXA2, which subsequently reveals a ligand binding site that is specific for fibrinogen, von Willebrand factor (vWF), fibronectin, and vitronectin. This conformational change is crucial for platelet-platelet adhesion. Ligand bound gpIIb/IIIa complex promotes platelet aggregation. This complex plays an imp |
| Immunogen | Human platelets |
| Other Names | gpIIb/IIIa complex, integrin αIIbβ3 |
| Gene, Accession # | Gene ID: 3674, 3690 |
| Catalog # | 362802 |
| Price | $229 |
| Order / More Info | Human CD41/CD61 Antibody from BIOLEGEND |
| Product Specific References | PubMed: 26292217, 27670775 |
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