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Antigenic Specificity | CRK |
Clone | W20038C |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-CRK. Adapter protein CRK, also known as CRK proto-oncogene adaptor protein or V-CRK avian sarcoma virus CT10 oncogene homolog, has two isoforms: CRKI (28 kD) and CRKII (40 kD). Closely associated is CRKL, or CRK-like protein (36 kD). CRKII and CRKL possess a C-terminal SH3 domain and a regulatory tyrosine phosphorylation site that are lacking in CRKI. CRK's SH2 and SH3 domains serve as positive and negative regulators of transformation, respectively. CRK is vital to cell motility via activation of Ra |
Immunogen | Recombinant fragment of human CRK |
Other Names | CRK, CRKII, p38, V-CRK Avian Aarcoma Virus CT10 Oncogene Homolog, CRK proto-oncogene adaptor protein |
Gene, Accession # | Gene ID: 1398 |
Catalog # | 609352 |
Price | $347 |
Order / More Info | CRK Antibody from BIOLEGEND |
Product Specific References | n/a |