Description | PE/Cyanine7 anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 21765905, 23105138, 25512626, 26302932, 26718566, 26923586, 29118125, 29958800, 30352429, 29138841, 29958800, 29958800, 30568305, 31968246, 32478124, 32636834, 31495780, 31495780, 29499100, 32027039, 31984629, 33789089 |