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Antigenic Specificity | NOVA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-NOVA1. RNA binding-protein Nova-1(NOVA1) is a brain-specific splicing factor well conserved in vertebrates. It was first identified as an antigen in paraneoplastic opsoclonus-myoclonus ataxia (POMA), a disorder related to breast cancer and motor dysfunction. Nova1 binds to a specific sequence cluster in the brain to regulate neuronal pre-mRNA splicing. Nova1-binding sequences are 94% identical in vertebrates, suggesting the binding is sequence dependent. Nova1 null mice die postnatally from motor defic |
Immunogen | Recombinant NOVA1 (Ala295-Gly510) with two N-terminal tags. |
Other Names | RNA-binding protein Nova-1, Neuro-oncological ventral antigen 1, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, Ventral neuron-specific protein 1, Nova-1 |
Gene, Accession # | Gene ID: 4857 |
Catalog # | 860801 |
Price | $125 |
Order / More Info | NOVA1 Antibody from BIOLEGEND |
Product Specific References | n/a |