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Antigenic Specificity | FBXO7 |
Clone | W16207A |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-FBXO7. F-box only protein 7 (FBXO7) is involved in the ubiquitination process during protein degradation. FBXO7 is a subunit of the SCF (SKP1/cullin-1/F-box protein) complex. The scaffold proteins cullin-1 and SKP1, the RING subunit Rbx1 together with the substrate-recruiting subunit FBXO7 form a functional E3 ubiquitin ligase. FBXO7 is implicated in Parkinson's disease. In addition to reduced proteasome activity, loss of FBXO7 in mice leads to Parkinsonism-like phenotype. Human FBXO7 is mainly localiz |
Immunogen | Human FBXO7 recombinant protein (1-250 a.a.) expressed in E. coli. |
Other Names | F-box only protein 7 |
Gene, Accession # | Gene ID: 25793 |
Catalog # | 853502 |
Price | $288 |
Order / More Info | FBXO7 Antibody from BIOLEGEND |
Product Specific References | n/a |