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Antigenic Specificity | Cleaved PARP (Asp214) Recombinant |
Clone | QA17A17 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | PerCP-Cyanine5.5 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PerCP/Cyanine5.5 anti-Cleaved PARP (Asp214) Recombinant. PARP (ADP-Ribose) Polymerase (PARP) is a 113 kD nuclear protein important for mediating the normal cellular response to DNA damage and repair in response to environmental stress. PARP catalyzes the transfer of ADP-ribose units from NAD? to various nuclear proteins, including topoisomerases, histones, and PARP itself, by poly(ADP-ribosyl)ation. Following DNA damage, this protein is cleaved by ICE-like caspases, such as caspase-3 and -7. In humans, this PARP cleavage occurs between Asp214 and Gly2 |
Immunogen | Proprietary synthetic peptide |
Other Names | PARP1, Poly (ADP-ribose) polymerase, PPOL, ARTD1, ADPRT, EC 2.4.2, ADP-Ribosyltransferase (NAD+;Poly (ADP-Ribose) Polymerase), Poly (ADP-Ribose) Polymerase Family, Member 1, DNA ADP-Ribosyltransferase PARP1, Poly[ADP-Ribose] Synthase 1 |
Gene, Accession # | Gene ID: 142 |
Catalog # | 669906 |
Price | $422 |
Order / More Info | Cleaved PARP (Asp214) Recombinant Antibody from BIOLEGEND |
Product Specific References | n/a |