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Antigenic Specificity | Th-POK (ZFP-67) |
Clone | 11H11A14 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | allophycocyanin (APC) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-Th-POK (ZFP-67). Th-POK is a member of the BTB-POZ domain-containing zinc finger transcription factor family. It regulates gene expression during intrathymic T cell differentiation. A single autosomal recessive mutation of the Th-POK gene results in the absence of mature CD4 helper T cells, called helper-deficient (HD) phenotype. In Th-POK deficient mice, MHC class II restricted thymocytes are redirected to the CD8 T cell lineage. On the contrary, forced expression of Th-POK redirects MHC class I restricted th |
Immunogen | Partial human Th-POK recombinant protein (197-345 a.a.) |
Other Names | T-helper-inducing POZ/Krueppel-like factor, Zinc finger and BTB domain-containing protein 7B (ZBTB7B), Krueppel-related zinc finger protein (cKrox), Zinc finger protein 67 homolog (ZFP-67) |
Gene, Accession # | Gene ID: 51043 |
Catalog # | 656405 |
Price | $161 |
Order / More Info | Th-POK (ZFP-67) Antibody from BIOLEGEND |
Product Specific References | n/a |