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Antigenic Specificity | Human CD262 (DR5, TRAIL-R2) |
Clone | DJR2-4 (7-8) |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-human CD262 (DR5, TRAIL-R2). DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins. |
Immunogen | Extracellular domain of DR5-human IgG1 Fc fusion protein |
Other Names | TRAIL-R2, KILLER, TRICK2, TNFRSF10B, Ly98, CD262 |
Gene, Accession # | Gene ID: 8795 |
Catalog # | 307408 |
Price | $350 |
Order / More Info | Human CD262 (DR5, TRAIL-R2) Antibody from BIOLEGEND |
Product Specific References | PubMed: 27898737, 30745855, 30742128, 31114586, 33053346 |