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Antigenic Specificity | BIRC3 (C-IAP2) |
Clone | W17221A |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-BIRC3 (C-IAP2). Baculoviral IAP Repeat Containing Protein 3, or BIRC3, is a member of the Inhibitor of apoptosis (IAP) family of proteins initially characterized as a component of the TNFα receptor signaling complex. BIRC3 functions as an E3 ubiquitin ligase, polyubiqiutinating target proteins such as RIP kinases, caspases, TRAF1, and BCL10. Loss of BIRC3 results in a significant impairment of TNFα-mediated NF-κB activation signaling cascades. |
Immunogen | Partial recombinant protein corresponding to amino acids 355-604 of human BIRC |
Other Names | Baculoviral IAP Repeat Containing 3, Inhibitor Of Apoptosis Protein 1, Apoptosis Inhibitor 2, TNFR2-TRAF-Signaling Complex Protein 1, RNF49, MIHC, API2 |
Gene, Accession # | Gene ID: 330 |
Catalog # | 667701 |
Price | $101 |
Order / More Info | BIRC3 (C-IAP2) Antibody from BIOLEGEND |
Product Specific References | n/a |