Edit |   |
---|---|
Antigenic Specificity | Fyn |
Clone | FYN-59 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Fyn. Fyn is a 59 kD protein tyrosine kinase and a member of the src subfamily. There are two reported isoforms of Fyn; FynT found in T cells, B cells and thymocytes, and FynB found in neuronal cells. Fyn has been shown to control cell growth, interact with the p85 subunit of PI3K, control high affinity IgE receptor-mediated mast cell degranulation, and participate in neuronal cell signaling. Fyn can be activated by T cell receptor engagement or anti-CD3 ligation. Fyn is known to be modified by phosph |
Immunogen | Partial recombinant human Fyn (aa 7-176) expressed in E coli |
Other Names | Tyrosine kinase p59fyn, Protein-tyrosine kinase fyn, Proto-oncogene tyrosine-protein kinase fyn |
Gene, Accession # | Gene ID: 2534 |
Catalog # | 626502 |
Price | $265 |
Order / More Info | Fyn Antibody from BIOLEGEND |
Product Specific References | PubMed: 20974990, 20126650, 26747837, 32321761, 31840160 |