Edit |   |
---|---|
Antigenic Specificity | CD49b (Integrin α2) |
Clone | P1E6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified, azide-free |
Size | 100 µL |
Concentration | n/a |
Applications | IHC-F |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-CD49b (Integrin α2). CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocyto |
Immunogen | This monoclonal antibody was generated against human HT1080 fibrosarcoma cells. |
Other Names | ITGA2, collagen receptor, VLA-2 subunit alpha, platelet antigen Br, platelet glycoprotein Ia, platelet glycoprotein GPIa, CD49 antigen-like family member B, platelet membrane glycoprotein Ia, very late activation protein 2 receptor, alpha-2 sub |
Gene, Accession # | Gene ID: 3673 |
Catalog # | 910901 |
Price | $275 |
Order / More Info | CD49b (Integrin α2) Antibody from BIOLEGEND |
Product Specific References | n/a |