CD49b (Integrin α2) Antibody from BIOLEGEND

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Antigenic SpecificityCD49b (Integrin α2)
CloneP1E6
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, κ
Formatpurified, azide-free
Size100 µL
Concentrationn/a
ApplicationsIHC-F
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DescriptionPurified (azide-free) anti-CD49b (Integrin α2). CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocyto
ImmunogenThis monoclonal antibody was generated against human HT1080 fibrosarcoma cells.
Other NamesITGA2, collagen receptor, VLA-2 subunit alpha, platelet antigen Br, platelet glycoprotein Ia, platelet glycoprotein GPIa, CD49 antigen-like family member B, platelet membrane glycoprotein Ia, very late activation protein 2 receptor, alpha-2 sub
Gene, Accession #Gene ID: 3673
Catalog #910901
Price$275
Order / More InfoCD49b (Integrin α2) Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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