BACE1 (CO2 terminus) Antibody from BIOLEGEND
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| Antigenic Specificity | BACE1 (CO2 terminus) |
| Clone | polyclonal |
| Host Species | Guinea Pig |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Western Blot (WB), IP, ICC, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-BACE1 (CO2 terminus). Processing of the β-amyloid precursor protein (βAPP) by two endopeptidases, β and γ secretases generates the amyloidogenic peptide Aβ, a major factor in the etiology of Alzheimers disease. The beta secretase is a novel membrane bound aspartyl protease and cleaves the βAPP to generate the N-terminus of the Aβ domain. The membrane bound C-terminal fragment generated by the beta secretase cut is subsequently cleaved by the gamma secretase resulting in the generation and secretion of the Aβ. |
| Immunogen | n/a |
| Other Names | Beta-Secretase 1, Asp 2, Memapsin-2, App Beta-Secretase, Aspartyl Protease 2, Beta-Site App Cleaving Enzyme 1, Beta-Secretase 1 Precursor Variant 1, Transmembrane Aspartic Proteinase Asp2, Membrane-Associated Aspartic Protease 2, Amyloid Beta A4 |
| Gene, Accession # | Gene ID: 23621 |
| Catalog # | 840201 |
| Price | $419 |
| Order / More Info | BACE1 (CO2 terminus) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 30626721 |
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