Description | PE/Cyanine7 anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 22848688, 5917094, 26717145, 27906184, 28558649, 28923392, 28558649, 29302052, 29331015, 29331015, 30558630, 30665184, 29331015, 30564890, 32668238, 32668238, 32970634, 31959990, 32550269, 32102981 |